SARS-COV-2 INFECTION IN PATIENTS WITH INBORN ERRORS OF IMMUNITY DUE TO DNA REPAIR DEFECTS

SARS-CoV-2 infection in patients with inborn errors of immunity due to DNA repair defects

SARS-CoV-2 infection in patients with inborn errors of immunity due to DNA repair defects

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Clinical information on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with inborn errors of immunity (IEI) during the current Coronavirus disease 2019 (COVID-19) pandemic is still limited.Proper DNA repair machinery is required 132 for the development of the adaptive immune system, which provides specific and long-term protection against SARS-CoV-2.This review highlights the impact of SARS-CoV-2 infections on IEI patients with DNA repair disorders and summarizes susceptibility risk factors, pathogenic Facial Moisturizers mechanisms, clinical manifestations and management strategies of COVID-19 in this special patient population.

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